Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence
M Noda, H Takahashi, T Tanabe, M Toyosato… - Nature, 1982 - nature.com
M Noda, H Takahashi, T Tanabe, M Toyosato, Y Furutani, T Hirose, M Asai, S Inayama…
Nature, 1982•nature.comDNA sequences complementary to the Torpedo californica electroplax mRNA coding for the
α-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of
the cloned cDNA indicates that the precursor consists of 461 amino acids including a
prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic
determinants on the α-subunit molecule are discussed.
α-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of
the cloned cDNA indicates that the precursor consists of 461 amino acids including a
prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic
determinants on the α-subunit molecule are discussed.
Abstract
DNA sequences complementary to the Torpedo californica electroplax mRNA coding for the α-subunit precursor of the acetylcholine receptor were cloned. The nucleotide sequence of the cloned cDNA indicates that the precursor consists of 461 amino acids including a prepeptide of 24 amino acids. Possible sites for acetylcholine binding and antigenic determinants on the α-subunit molecule are discussed.
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