[HTML][HTML] Antibacterial activity of glycosylated and phosphorylated chromogranin A-derived peptide 173-194 from bovine adrenal medullary chromaffin granules
JM Strub, Y Goumon, K Lugardon, C Capon… - Journal of Biological …, 1996 - ASBMB
Recently, we have isolated from bovine chromaffin granules and identified two natural
peptides possessing antibacterial activity: secretolytin (chromogranin B 614-626) and
enkelytin (proenkephalin-A 209-237). Here, we characterize a large natural fragment,
corresponding to chromogranin A 79-431, that inhibits growth of both Gram-positive and
Gram-negative bacteria. The aim of the present work was to determine the shortest active
peptide located in the 79-431 chromogranin A region. Three peptides, which shared the …
peptides possessing antibacterial activity: secretolytin (chromogranin B 614-626) and
enkelytin (proenkephalin-A 209-237). Here, we characterize a large natural fragment,
corresponding to chromogranin A 79-431, that inhibits growth of both Gram-positive and
Gram-negative bacteria. The aim of the present work was to determine the shortest active
peptide located in the 79-431 chromogranin A region. Three peptides, which shared the …