Effectiveness of oseltamivir in preventing influenza in household contacts: a randomized controlled trial

R Welliver, AS Monto, O Carewicz, E Schatteman… - Jama, 2001 - jamanetwork.com
ContextInfluenza virus is easily spread among the household contacts of an infected person,
and prevention of influenza in household contacts can control spread of influenza in the
community. ObjectiveTo investigate the efficacy of oseltamivir in preventing spread of
influenza to household contacts of influenza-infected index cases (ICs). Design and
SettingRandomized, double-blind, placebo-controlled study conducted at 76 centers in
North America and Europe during the winter of 1998-1999. ParticipantsThree hundred …