We have studied the risk of progression to active pulmonary tuberculosis (TB) among a
population of Cambodian rural poor suffering from one of the highest global incidences of
TB. Together with a community-based TB program, we have established a research
partnership that has demonstrated the association of a particular HLA binding motif and
progression to active pulmonary TB. We have also shown that candidate gene
polymorphisms are ethnic specific and unique in Cambodia and are likely markers for as yet …