A polymorphic DNA marker genetically linked to Huntington's disease
JF Gusella, NS Wexler, PM Conneally, SL Naylor… - Nature, 1983 - nature.com
JF Gusella, NS Wexler, PM Conneally, SL Naylor, MA Anderson, RE Tanzi, PC Watkins…
Nature, 1983•nature.comFamily studies show that the Huntington's disease gene is linked to a polymorphic DNA
marker that maps to human chromosome 4. The chromosomal localization of the
Huntington's disease gene is the first step in using recombinant DNA technology to identify
the primary genetic defect in this disorder.
marker that maps to human chromosome 4. The chromosomal localization of the
Huntington's disease gene is the first step in using recombinant DNA technology to identify
the primary genetic defect in this disorder.
Abstract
Family studies show that the Huntington's disease gene is linked to a polymorphic DNA marker that maps to human chromosome 4. The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.
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