[HTML][HTML] Obesity: the integrated roles of environment and genetics

JR Speakman - The Journal of nutrition, 2004 - Elsevier
Obesity represents one of the most serious global health issues with∼ 310 million people
presently affected. It develops because of a mismatch between energy intake and
expenditure that results from behavior (feeding behavior and time spent active) and
physiology (resting metabolism and expenditure when active). Both of these traits are
affected by environmental and genetic factors. The dramatic increase in the numbers of
obese people in Western societies reflects mostly changing environmental factors and is …