FIG. 1. ELECTROPHORETIC PATTERNS liopathic grand mal (normal) A Spinal fluid nxiety state (normal) C Spinal fluid ymphopathia venereum E Spinal fluid lultiple myeloma G Spinal fluid-Multiple sclerosis I Spinal fluid 655751 Neurosyphilis 635202-Diabetic neuritis 652371-Left frontal cystic astrocytoma mized by maintaining the mean temperature (temperature is highest at center and lowest at walls of cells) of the solution at the point where the change of density with temperature is least (temperature of maximum density). Convection limits the wattage which may be dissipated in the cell.

The current produces an electrical field throughout the cell. If the cell has a uniform cross-sectional area, Acm', the field E equals IIKA where I is the current in amperes and K is the specific conductivity of the solution in reciprocal ohms. This electrical field causes the different protein components of the solution to migrate at a rate proportional to the statistical surface charge per unit area of the particles or molecules, and in a direction determined by the sign of this charge. This rate of migration, in cm. persecond per unit field in volts per cm., is designated as the mobility of the component. Bending of light rays caused by concentration gradients at the boundaries of each component may be detected by various optical methods; in this study, the Toepler" Schlieren" method, as modified by Longsworth (5), was used. With this method each electrophoretically distinct