AGA technical review on nonalcoholic fatty liver disease

AJ Sanyal - Gastroenterology, 2002 - Elsevier
Gastroenterology, 2002Elsevier
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of conditions characterized
histologically by mainly macrovesicular hepatic steatosis and occurs in those who do not
consume alcohol in amounts generally considered to be harmful to the liver. There are 2
histologic patterns of NAFLD: fatty liver alone and steatohepatitis. NAFLD is an increasingly
recognized cause of liver-related morbidity and mortality. In this review, the existing literature
regarding the nomenclature, clinical and histologic spectrum, natural history, diagnosis, and …
Abstract
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of conditions characterized histologically by mainly macrovesicular hepatic steatosis and occurs in those who do not consume alcohol in amounts generally considered to be harmful to the liver. There are 2 histologic patterns of NAFLD: fatty liver alone and steatohepatitis. NAFLD is an increasingly recognized cause of liver-related morbidity and mortality. In this review, the existing literature regarding the nomenclature, clinical and histologic spectrum, natural history, diagnosis, and management of this condition are discussed.
GASTROENTEROLOGY 2002;123:1705-1725
Elsevier