Prognostic value of pololike kinase expression in melanomas
K Strebhardt, L Kneisel, C Linhart, A Bernd… - Jama, 2000 - jamanetwork.com
Methods To examine the prognostic significance of PLK expression in melanomas, we
investigated 175 patients (94 female, 81 male) with superficial spreading melanomas (134),
nodular melanomas (31), lentigo maligna melanomas (7), and acrolentiginous melanomas
(3), with a median thickness of 0.75 mm (range, 0.1-8.0 mm; mean, 1.17 mm). Paraffin-
embedded skin sections of primary tumors were immunolabeled with monoclonal antibodies
against PLK (Zymed Laboratories Inc, San Francisco, Calif) and Ki-67 (Dianova, Germany) …
investigated 175 patients (94 female, 81 male) with superficial spreading melanomas (134),
nodular melanomas (31), lentigo maligna melanomas (7), and acrolentiginous melanomas
(3), with a median thickness of 0.75 mm (range, 0.1-8.0 mm; mean, 1.17 mm). Paraffin-
embedded skin sections of primary tumors were immunolabeled with monoclonal antibodies
against PLK (Zymed Laboratories Inc, San Francisco, Calif) and Ki-67 (Dianova, Germany) …