[HTML][HTML] Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface
M de la Llera-Moya, GH Rothblat, MA Connelly… - Journal of lipid …, 1999 - ASBMB
In addition to its effect on high density lipoprotein (HDL) cholesteryl ester (CE) uptake,
scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux
from Chinese hamster ovary (CHO) cells stably expressing mouse SR-BI, a novel function of
SR-BI that may play a role in cholesterol removal from the vessel wall where the receptor
can be found. It is possible that SR-BI stimulates flux simply by tethering acceptor HDL
particles in close apposition to the cell surface thereby facilitating the movement of …
scavenger receptor BI (SR-BI) was recently reported to stimulate free cholesterol (FC) flux
from Chinese hamster ovary (CHO) cells stably expressing mouse SR-BI, a novel function of
SR-BI that may play a role in cholesterol removal from the vessel wall where the receptor
can be found. It is possible that SR-BI stimulates flux simply by tethering acceptor HDL
particles in close apposition to the cell surface thereby facilitating the movement of …
