[HTML][HTML] SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells
NR Webb, PM Connell, GA Graf, EJ Smart… - Journal of Biological …, 1998 - ASBMB
The scavenger receptor class B, type I (SR-BI), binds high density lipoprotein (HDL) and
mediates selective uptake of cholesteryl ester from HDL and HDL-dependent cholesterol
efflux from cells. We recently identified a new mRNA variant that differs from the previously
characterized form in that the encoded C-terminal cytoplasmic domain is almost completely
different. In the present study, we demonstrate that the mRNAs for mouse SR-BI and SR-BII
(previously termed SR-BI. 2) are the alternatively spliced products of a single gene. The …
mediates selective uptake of cholesteryl ester from HDL and HDL-dependent cholesterol
efflux from cells. We recently identified a new mRNA variant that differs from the previously
characterized form in that the encoded C-terminal cytoplasmic domain is almost completely
different. In the present study, we demonstrate that the mRNAs for mouse SR-BI and SR-BII
(previously termed SR-BI. 2) are the alternatively spliced products of a single gene. The …