[HTML][HTML] Scavenger receptor class B, type I-mediated [3H] cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor
X Gu, K Kozarsky, M Krieger - Journal of Biological Chemistry, 2000 - ASBMB
The murine scavenger receptor class B, type I (mSR-BI) is a receptor for high density
lipoprotein (HDL), low density lipoprotein (LDL), and acetylated LDL (AcLDL). It mediates
selective uptake of lipoprotein lipid and stimulates efflux of [3 H] cholesterol to lipoproteins.
SR-BI-mediated [3 H] cholesterol efflux was proposed to be independent of ligand binding.
In this study, using anti-mSR-BI antibody KKB-1 and two mSR-BI mutants with altered ligand
binding properties, we demonstrated that SR-BI-mediated [3 H] cholesterol efflux to …
lipoprotein (HDL), low density lipoprotein (LDL), and acetylated LDL (AcLDL). It mediates
selective uptake of lipoprotein lipid and stimulates efflux of [3 H] cholesterol to lipoproteins.
SR-BI-mediated [3 H] cholesterol efflux was proposed to be independent of ligand binding.
In this study, using anti-mSR-BI antibody KKB-1 and two mSR-BI mutants with altered ligand
binding properties, we demonstrated that SR-BI-mediated [3 H] cholesterol efflux to …