Objective To determine the effects of bexarotene on malignant T cells isolated from the
peripheral blood of patients with the leukemic variant of cutaneous T-cell lymphoma (Sézary
syndrome). Design, Setting, and Participants Peripheral blood mononuclear cells from 9
patients with Sézary syndrome and a high burden of circulating malignant T cells (> 50% of
peripheral blood mononuclear cells) and 6 healthy volunteers underwent evaluation at a
university medical center, to test the effects of bexarotene on T cells. Main Outcome …