[HTML][HTML] Direct Association between the Ret Receptor Tyrosine Kinase and the Src Homology 2-containing Adapter Protein Grb7 (∗)
A Pandey, X Liu, JE Dixon, PP Di Fiore… - Journal of Biological …, 1996 - ASBMB
Adapter proteins containing Src homology 2 (SH2) domains link transmembrane receptor
protein-tyrosine kinases to downstream signal transducing molecules. A family of SH2
containing adapter proteins including Grb7 and Grb10 has been recently identified. We had
previously shown that Grb10 associates with Ret via its SH2 domain in an activation-
dependent manner (Pandey, A., Duan, H., Di Fiore, PP, and Dixit, VM (1995) J. Biol. Chem.
270, 21461-21463). We now demonstrate that the related adapter molecule Grb7 also …
protein-tyrosine kinases to downstream signal transducing molecules. A family of SH2
containing adapter proteins including Grb7 and Grb10 has been recently identified. We had
previously shown that Grb10 associates with Ret via its SH2 domain in an activation-
dependent manner (Pandey, A., Duan, H., Di Fiore, PP, and Dixit, VM (1995) J. Biol. Chem.
270, 21461-21463). We now demonstrate that the related adapter molecule Grb7 also …