Protection from HIV/AIDS: the importance of innate immunity
JA Levy, I Scott, C Mackewicz - Clinical Immunology, 2003 - Elsevier
Infection by HIV can occur through intimate sexual activity, contact with contaminated blood
or blood products, and transmission from mother to child [1]. Importantly, the virus is
infectious as a free particle or in association with virus-infected cells. The latter entity is
found in genital fluids at greater quantities than free infectious virions [2]. In seminal fluid, for
example, the amount of infectious virus may be 40–50 particles/ml, whereas infected cells
may be present at the level of 5% of all white blood cells in a normal ejaculate (generally …
or blood products, and transmission from mother to child [1]. Importantly, the virus is
infectious as a free particle or in association with virus-infected cells. The latter entity is
found in genital fluids at greater quantities than free infectious virions [2]. In seminal fluid, for
example, the amount of infectious virus may be 40–50 particles/ml, whereas infected cells
may be present at the level of 5% of all white blood cells in a normal ejaculate (generally …