Levels of antimicrobial molecules defensin and lactoferrin are elevated in the cerebrospinal fluid of children with meningitis
FA Maffei, RP Heine, MJ Whalen, LF Mortimer… - …, 1999 - publications.aap.org
Objective: To measure levels of defensins and lactoferrin in the cerebrospinal fluid (CSF) of
children with meningitis. Study Design. Prospective descriptive study involving children
undergoing lumbar puncture during evaluation for meningitis. Methods. CSF concentrations
of defensins and lactoferrin were determined using enzyme-linked immunosorbent assays
on 19 children with bacterial meningitis, 31 children with aseptic meningitis, and 32 control
children found to have normal CSF during evaluation for meningitis. Pertinent clinical and …
children with meningitis. Study Design. Prospective descriptive study involving children
undergoing lumbar puncture during evaluation for meningitis. Methods. CSF concentrations
of defensins and lactoferrin were determined using enzyme-linked immunosorbent assays
on 19 children with bacterial meningitis, 31 children with aseptic meningitis, and 32 control
children found to have normal CSF during evaluation for meningitis. Pertinent clinical and …