Plasma defensin concentrations are elevated in patients with septicemia or bacterial meningitis
AV Panyutich, EA Panyutich… - The Journal of …, 1993 - translationalres.com
We measured concentrations of defensins (human neutrophil peptides) in the plasma of
healthy volunteers and patients with sepsis and meningitis. When a sensitive enzyme
immunoassay was used, defensins were detected in plasma samples from 13 of 24 healthy
blood donors, with a mean±SD of 42±53 ng/ml. Defensin levels in plasma samples from
seven patients with sepsis at the onset of disease ranged from 900 ng/ml to 170,000 ng/ml.
In 10 patients with meningitis in the initial phase of disease, plasma defensin concentrations …
healthy volunteers and patients with sepsis and meningitis. When a sensitive enzyme
immunoassay was used, defensins were detected in plasma samples from 13 of 24 healthy
blood donors, with a mean±SD of 42±53 ng/ml. Defensin levels in plasma samples from
seven patients with sepsis at the onset of disease ranged from 900 ng/ml to 170,000 ng/ml.
In 10 patients with meningitis in the initial phase of disease, plasma defensin concentrations …