Evaluation of essential tremor with multi-voxel magnetic resonance spectroscopy

FL Pagan, JA Butman, JM Dambrosia, M Hallett - Neurology, 2003 - AAN Enterprises
FL Pagan, JA Butman, JM Dambrosia, M Hallett
Neurology, 2003AAN Enterprises
The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10
patients with ET and 10 volunteers using a multislice MR spectroscopy imaging sequence.
Left and right cerebellar hemisphere NAA/CR and NAA/Cho ratios were significantly smaller
in the ET patients than healthy subjects. The authors' data suggest that the decreased
NAA/Cr and NAA/Cho ratios within the cerebellum may represent an abnormality in
neuronal function.
The pathologic substrate of essential tremor (ET) remains unknown. The authors studied 10 patients with ET and 10 volunteers using a multislice MR spectroscopy imaging sequence. Left and right cerebellar hemisphere NAA/CR and NAA/Cho ratios were significantly smaller in the ET patients than healthy subjects. The authors’ data suggest that the decreased NAA/Cr and NAA/Cho ratios within the cerebellum may represent an abnormality in neuronal function.
American Academy of Neurology