[HTML][HTML] Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4
HD Youn, CM Grozinger, JO Liu - Journal of Biological Chemistry, 2000 - ASBMB
The myocyte enhancer factor 2 (MEF2) consists of a family of transcription factors that play
important roles in a number of physiological processes from muscle cell differentiation to
neuronal survival and T cell apoptosis. MEF2 has been reported to be associated with
several distinct repressors including Cabin1 (cain), MEF2-interacting transcriptional
repressor (MITR), and HDAC4. It has been previously shown that Cabin1 is associated with
MEF2 in a calcium-sensitive manner; activated calmodulin binds to Cabin1 and releases it …
important roles in a number of physiological processes from muscle cell differentiation to
neuronal survival and T cell apoptosis. MEF2 has been reported to be associated with
several distinct repressors including Cabin1 (cain), MEF2-interacting transcriptional
repressor (MITR), and HDAC4. It has been previously shown that Cabin1 is associated with
MEF2 in a calcium-sensitive manner; activated calmodulin binds to Cabin1 and releases it …