[HTML][HTML] Substitution of the degenerate smooth muscle (SM) α-actin CC (A/T-rich) 6GG elements with c-fos serum response elements results in increased basal …
MB Hautmann, CS Madsen, CP Mack… - Journal of Biological …, 1998 - ASBMB
We have previously demonstrated that both CC (A/T-rich) 6 GG (CArG) elements A and B of
the smooth muscle (SM) α-actin promoter are required for smooth muscle cell (SMC)-specific
expression and angiotensin II (AII)-induced stimulation. Moreover, results provided evidence
that AII responsiveness of SM α-actin was at least partially dependent on modulation of
serum response factor (SRF) binding to the SM α-actin CArGs by the homeodomain
containing protein, MHox. The goal of the present study was to investigate whether the …
the smooth muscle (SM) α-actin promoter are required for smooth muscle cell (SMC)-specific
expression and angiotensin II (AII)-induced stimulation. Moreover, results provided evidence
that AII responsiveness of SM α-actin was at least partially dependent on modulation of
serum response factor (SRF) binding to the SM α-actin CArGs by the homeodomain
containing protein, MHox. The goal of the present study was to investigate whether the …