Two experimental thrombosis models in rats have been compared with regard to the
composition of the formed thrombi and the effects of various treatments on thrombus
formation. In the first model thrombosis is induced in the vena cava by a combination of
venous stasis and hypercoagulability; these thrombi consist merely of red cells and fibrin
with only a few platelets. In the second model thrombosis is induced in an arterio-venous
shunt in which the formed thrombi consist of red cells, fibrin and a large amount of platelet …