Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
ME Greenberg, EB Ziff - Nature, 1984 - nature.com
ME Greenberg, EB Ziff
Nature, 1984•nature.comTranscription of the c-fos proto-oncogene is greatly increased within minutes of
administering purified growth factors to quiescent 3T3 cells. This stimulation is the most
rapid transcriptional response to peptide growth factors yet described, and implies a role for
c-fos in cell-cycle control Transformation by c-fos may result from a temporal deregulation of
this control.
administering purified growth factors to quiescent 3T3 cells. This stimulation is the most
rapid transcriptional response to peptide growth factors yet described, and implies a role for
c-fos in cell-cycle control Transformation by c-fos may result from a temporal deregulation of
this control.
Abstract
Transcription of the c-fos proto-oncogene is greatly increased within minutes of administering purified growth factors to quiescent 3T3 cells. This stimulation is the most rapid transcriptional response to peptide growth factors yet described, and implies a role for c-fos in cell-cycle control Transformation by c-fos may result from a temporal deregulation of this control.
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