Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects
MJ Cushley, AE Tattersfield… - British journal of clinical …, 2004 - ncbi.nlm.nih.gov
MJ Cushley, AE Tattersfield, ST Holgate
British journal of clinical pharmacology, 2004•ncbi.nlm.nih.govMethods Six normal non-allergic, six allergic asthmatic and seven non-allergic asthmatic
subjects, whose clinical details arc summarised in Table 1, were studied All subjects gave
their informed consent and the study was approved by the local Ethical Committee.
Asthmatic subjects omitted bronchodilators and sodium crúmoglycate fur 8 h prior to each
visit. Forced expiratory volume in 1 s (FEV;) varied by less than 12% and specific airway
conductance (sGaw) by less than 15% between study days. The purine nucleosides and …
subjects, whose clinical details arc summarised in Table 1, were studied All subjects gave
their informed consent and the study was approved by the local Ethical Committee.
Asthmatic subjects omitted bronchodilators and sodium crúmoglycate fur 8 h prior to each
visit. Forced expiratory volume in 1 s (FEV;) varied by less than 12% and specific airway
conductance (sGaw) by less than 15% between study days. The purine nucleosides and …
Methods
Six normal non-allergic, six allergic asthmatic and seven non-allergic asthmatic subjects, whose clinical details arc summarised in Table 1, were studied All subjects gave their informed consent and the study was approved by the local Ethical Committee. Asthmatic subjects omitted bronchodilators and sodium crúmoglycate fur 8 h prior to each visit. Forced expiratory volume in 1 s (FEV;) varied by less than 12% and specific airway conductance (sGaw) by less than 15% between study days. The purine nucleosides and saline were administered as© 19ЙЗ Blackwell Scientific Publications i 2004 Blackwell Publishing Ltd Br J Clin Pharmacol 58: 7 S751-S755 S751
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