[HTML][HTML] Mouse ephrinB3 augments T-cell signaling and responses to T-cell receptor ligation
G Yu, H Luo, Y Wu, J Wu - Journal of Biological Chemistry, 2003 - ASBMB
Ephrins (EFN) are cell-surface ligands of Ephs, the largest family of cell-surface receptor
tyrosine kinases. The function of EFNs in the immune system has not been well studied,
although some EFNs and Ephs are expressed at high levels on certain leukocytes. We
report here that EFNB3 and its receptors (collectively called EFNB3Rs, as EFNB3 binds to
multiple EphBs) were expressed in peripheral T cells and monocytes/macrophages, with T
cells being the dominant EFNB3+ and EFNB3R+ cell type. Solid-phase EFNB3-Fc in the …
tyrosine kinases. The function of EFNs in the immune system has not been well studied,
although some EFNs and Ephs are expressed at high levels on certain leukocytes. We
report here that EFNB3 and its receptors (collectively called EFNB3Rs, as EFNB3 binds to
multiple EphBs) were expressed in peripheral T cells and monocytes/macrophages, with T
cells being the dominant EFNB3+ and EFNB3R+ cell type. Solid-phase EFNB3-Fc in the …