The effect of α-lipoic acid on the neurovascular reflex arc in patients with diabetic neuropathy assessed by capillary microscopy
ES Haak, KH Usadel, M Kohleisen, A Yilmaz… - Microvascular …, 1999 - Elsevier
Patients with diabetic polyneuropathy are known to have an impaired neurovascular reflex
arc compared to healthy controls. This is seen in a delayed decrease in microcirculation of
the ipsilateral hand after cooling of the contralateral hand. The aim of this pilot study was to
investigate whether intravenous α-lipoic acid (ALA)(Thioctacid, Asta Medica) therapy might
be able to improve this impaired neurovascular reflex arc in patients with diabetic
neuropathy. In addition, clinical effects were evaluated with the aid of the neuropathy …
arc compared to healthy controls. This is seen in a delayed decrease in microcirculation of
the ipsilateral hand after cooling of the contralateral hand. The aim of this pilot study was to
investigate whether intravenous α-lipoic acid (ALA)(Thioctacid, Asta Medica) therapy might
be able to improve this impaired neurovascular reflex arc in patients with diabetic
neuropathy. In addition, clinical effects were evaluated with the aid of the neuropathy …