[HTML][HTML] Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation: up-regulated expression with …

G Ferry, E Tellier, A Try, S Grés, I Naime… - Journal of Biological …, 2003 - ASBMB
Our group has recently demonstrated (Gesta, S., Simon, M., Rey, A., Sibrac, D., Girard, A.,
Lafontan, M., Valet, P., and Saulnier-Blache, JS (2002) J. Lipid Res. 43, 904–910) the
presence, in adipocyte conditioned-medium, of a soluble lysophospholipased-activity
(LPLDact) involved in synthesis of the bioactive phospholipid lysophosphatidic acid (LPA).
In the present report, LPLDact was purified from 3T3F442A adipocyte-conditioned medium
and identified as the type II ecto-nucleotide pyrophosphatase phosphodiesterase, autotaxin …