The hunting of the Src
GS Martin - Nature reviews Molecular cell biology, 2001 - nature.com
GS Martin
Nature reviews Molecular cell biology, 2001•nature.comThe non-receptor tyrosine kinase Src is important for many aspects of cell physiology. The
viral src gene was the first retroviral oncogene to be identified, and its cellular counterpart
was the first proto-oncogene to be discovered in the vertebrate genome. Src has been
important, not only as an object of study in itself, but also as an entry point into the molecular
genetics of cancer.
viral src gene was the first retroviral oncogene to be identified, and its cellular counterpart
was the first proto-oncogene to be discovered in the vertebrate genome. Src has been
important, not only as an object of study in itself, but also as an entry point into the molecular
genetics of cancer.
Abstract
The non-receptor tyrosine kinase Src is important for many aspects of cell physiology. The viral src gene was the first retroviral oncogene to be identified, and its cellular counterpart was the first proto-oncogene to be discovered in the vertebrate genome. Src has been important, not only as an object of study in itself, but also as an entry point into the molecular genetics of cancer.
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