A case of Guillain-Barré syndrome following a family outbreak of Campylobacter jejuni enteritis

CW Ang, PA Van Doorn, HP Endtz, ISJ Merkies… - Journal of …, 2000 - Elsevier
We describe an outbreak of Campylobacter jejuni enteritis involving three family members of
whom one developed Guillain–Barré syndrome (GBS). The patients' serum reacted strongly
with several gangliosides and with the lipopolysaccharide (LPS) fractions from the C. jejuni
strains isolated from his family members. Only low titer anti-ganglioside antibodies were
found in his siblings. HLA-typing did not indicate a locus associated with auto-antibody
production. Comparing the immune response in GBS patients and C. jejuni enteritis patients …