[PDF][PDF] Stem cell plasticity?

J Frisén - Neuron, 2002 - cell.com
J Frisén
Neuron, 2002cell.com
Cells differentiate according to stereotype pedigrees, or at least so we thought. Several
studies have challenged this dogma and suggested that stem cells in several tissues may be
plastic and switch lineages, but many of the results are open to other interpretations. Is there
solid evidence for stem cell plasticity and should we rewrite the textbooks just yet?
Abstract
Cells differentiate according to stereotype pedigrees, or at least so we thought. Several studies have challenged this dogma and suggested that stem cells in several tissues may be plastic and switch lineages, but many of the results are open to other interpretations. Is there solid evidence for stem cell plasticity and should we rewrite the textbooks just yet?
cell.com