Electron microscopic demonstrations of filamentous molecular sieve plugs in capillary fenestrae

J Rostgaard, K Qvortrup - Microvascular research, 1997 - Elsevier
The permeability of capillaries is usually explained with reference to “small pores,”
permeable to water and small solutes, and “large pores,” permeable to proteins. Fenestrated
capillaries are far more permeable to water and small solutes than nonfenestrated
capillaries; moreover, the permeability is highest in the capillaries with the most fenestrae.
This suggests that the small pores reside in the fenestral diaphragms; however, no such
pores have been illustrated using electron microscopy. In an attempt to clarify this …