Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+ T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells …
SR Durham, S Ying, VA Varney, MR Jacobson… - Journal of allergy and …, 1996 - Elsevier
BACKGROUND: Grass pollen injection immunotherapy is effective in patients with summer
hay fever, although efficacy must be balanced against possible side effects. The mechanism
of immunotherapy is unknown but may be related to its ability to inhibit allergen-induced late
responses, which are known to be characterized by infiltration of T lymphocytes, eosinophils,
and cells with messenger RNA for so-called TH2-type cytokines (IL-4 and IL-5). OBJECTIVE:
This study was designed to observe the effect of grass pollen immunotherapy on late nasal …
hay fever, although efficacy must be balanced against possible side effects. The mechanism
of immunotherapy is unknown but may be related to its ability to inhibit allergen-induced late
responses, which are known to be characterized by infiltration of T lymphocytes, eosinophils,
and cells with messenger RNA for so-called TH2-type cytokines (IL-4 and IL-5). OBJECTIVE:
This study was designed to observe the effect of grass pollen immunotherapy on late nasal …