Development and function of T helper 1 cells
A O'Garra, D Robinson - Advances in immunology, 2004 - Elsevier
Publisher Summary The immune system has developed to be highly specialized and
effective in eradicating a wide variety of pathogens with minimum immunopathology. The
adaptive arm of the immune response, consisting of antigen-specific T and B cells, interacts
with cells of the innate immune system to mediate an effective response to infectious
pathogens. Heterogeneity of T cell responses to pathogens can determine the resistance or
susceptibility of a host to such infectious agents. T helper 1 cells have been also implicated …
effective in eradicating a wide variety of pathogens with minimum immunopathology. The
adaptive arm of the immune response, consisting of antigen-specific T and B cells, interacts
with cells of the innate immune system to mediate an effective response to infectious
pathogens. Heterogeneity of T cell responses to pathogens can determine the resistance or
susceptibility of a host to such infectious agents. T helper 1 cells have been also implicated …