[HTML][HTML] Suppressor T cells in human diseases
C Baecher-Allan, DA Hafler - The Journal of experimental medicine, 2004 - ncbi.nlm.nih.gov
C Baecher-Allan, DA Hafler
The Journal of experimental medicine, 2004•ncbi.nlm.nih.govAlthough central and peripheral tolerance are important for the regulation of human immune
responses to self-and microbial antigens, an important role of suppressor CD4+ CD25+ T
cells is suggested from the recent investigations of human autoimmune diseases and HIV.
These new data provide increasing evidence that altered function of CD4+ CD25+ T cells
may be an important factor in a wide range of human inflammatory and infectious diseases.
responses to self-and microbial antigens, an important role of suppressor CD4+ CD25+ T
cells is suggested from the recent investigations of human autoimmune diseases and HIV.
These new data provide increasing evidence that altered function of CD4+ CD25+ T cells
may be an important factor in a wide range of human inflammatory and infectious diseases.
Abstract
Although central and peripheral tolerance are important for the regulation of human immune responses to self-and microbial antigens, an important role of suppressor CD4+ CD25+ T cells is suggested from the recent investigations of human autoimmune diseases and HIV. These new data provide increasing evidence that altered function of CD4+ CD25+ T cells may be an important factor in a wide range of human inflammatory and infectious diseases.
ncbi.nlm.nih.gov