Human blastocysts from aggregated mononucleated cells of two or more non-viable zygote-derived embryos
M Alikani, SM Willadsen - Reproductive biomedicine online, 2002 - Elsevier
This study examined the developmental capacity of aggregates of surviving mono-nucleated
cells isolated from several non-viable human embryos on day 3 or day 4 after fertilization.
The results clearly demonstrate that some blastomeres from non-viable embryos do indeed
maintain their developmental potential and regulatory capacity to the extent of being able to
contribute to a normally organized blastocyst, with as many as 90% diploid cells. Although
the chimaeric nature of such blastocysts excludes them from use in therapeutic IVF, they are …
cells isolated from several non-viable human embryos on day 3 or day 4 after fertilization.
The results clearly demonstrate that some blastomeres from non-viable embryos do indeed
maintain their developmental potential and regulatory capacity to the extent of being able to
contribute to a normally organized blastocyst, with as many as 90% diploid cells. Although
the chimaeric nature of such blastocysts excludes them from use in therapeutic IVF, they are …