[HTML][HTML] What brings pericytes to tumor vessels?
RK Jain, MF Booth - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
RK Jain, MF Booth
The Journal of clinical investigation, 2003•Am Soc Clin InvestigParacrine signaling via platelet-derived growth factor B (PDGFB), expressed by endothelial
cells, and its receptor PDGFR-β, expressed by pericytes, plays a central role in blood vessel
maturation. A new study reveals that it is not just the presence of PDGFB, but how it is
presented to pericytes, that determines the quality of the endothelium-pericyte interaction.
cells, and its receptor PDGFR-β, expressed by pericytes, plays a central role in blood vessel
maturation. A new study reveals that it is not just the presence of PDGFB, but how it is
presented to pericytes, that determines the quality of the endothelium-pericyte interaction.
Paracrine signaling via platelet-derived growth factor B (PDGFB), expressed by endothelial cells, and its receptor PDGFR-β, expressed by pericytes, plays a central role in blood vessel maturation. A new study reveals that it is not just the presence of PDGFB, but how it is presented to pericytes, that determines the quality of the endothelium-pericyte interaction.
The Journal of Clinical Investigation