[HTML][HTML] Overexpression of Monomeric and Multimeric GIRK4 Subunits in Rat Atrial Myocytes Removes Fast Desensitization and Reduces Inward Rectification of …
K Bender, MC Wellner-Kienitz, A Inanobe… - Journal of Biological …, 2001 - ASBMB
K+ channels composed of G-protein-coupled inwardly rectifying K+ channel (GIRK)(Kir3. 0)
subunits are expressed in cardiac, neuronal, and various endocrine tissues. They are
involved in inhibiting excitability and contribute to regulating important physiological
functions such as cardiac frequency and secretion of hormones. The functional cardiac (K
(ACh)) channel activated by G i/G o-coupled receptors such as muscarinic M 2 or purinergic
A 1 receptors is supposed to be composed of the subunits GIRK1 and GIRK4 in a …
subunits are expressed in cardiac, neuronal, and various endocrine tissues. They are
involved in inhibiting excitability and contribute to regulating important physiological
functions such as cardiac frequency and secretion of hormones. The functional cardiac (K
(ACh)) channel activated by G i/G o-coupled receptors such as muscarinic M 2 or purinergic
A 1 receptors is supposed to be composed of the subunits GIRK1 and GIRK4 in a …