The prognosis of renal survival in both type 1 and type 2 diabetes mellitus is not benign.
Several factors characterize the increase in the risk of developing renal damage in diabetic
patients, distinguished in diabetes-related factors, genetic factors and other factors.
Diagnosis: Diagnosis requires standard annual urinalysis and dipstick for albumin. In
patients with negative urine dipstick, the routine approach is to evaluate the
albumin/creatinine ratio (ACR) in the first voided urine. The degree of renal impairment is …

Genetic aspects of diabetic nephropathy. Background Diabetic nephropathy from type 2
diabetes mellitus is the most common cause of end-stage renal disease (ESRD) in the
United States and in Western Europe. Although patients with overt nephropathy generally
experience greater cumulative glycemic exposure, the difference in glycemic control
between patients developing nephropathy compared to those who did not, could not be
demonstrated. This observation is consistent with the notion that perhaps other factors, in …