Unraveling the secrets of single donor success in islet transplantation
AMJ Shapiro, C Ricordi - American Journal of Transplantation, 2004 - amjtransplant.org
Islet transplantation is emerging as an attractive alternative to solitary pancreas
transplantation for a highly select group of patients with severe, labile forms of Type 1
diabetes that had previously tried and failed on intensive insulin therapy. The year 2000
marked a dramatic shift in clinical success with the introduction of the so-called 'Edmonton
Protocol', which built upon many years of intensive research and extensive collaborations
between islet groups worldwide (1, 2). With cumulative combined data in more than 75 islet …
transplantation for a highly select group of patients with severe, labile forms of Type 1
diabetes that had previously tried and failed on intensive insulin therapy. The year 2000
marked a dramatic shift in clinical success with the introduction of the so-called 'Edmonton
Protocol', which built upon many years of intensive research and extensive collaborations
between islet groups worldwide (1, 2). With cumulative combined data in more than 75 islet …