Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits

T Esaki, T Hayashi, E Muto, K Yamada, M Kuzuya… - Atherosclerosis, 1997 - Elsevier
While endothelial nitric oxide synthase has been reported to be expressed in the endothelial
cells of normal and atherosclerotic vessels, there are few reports about inducible nitric oxide
synthase (iNOS). We investigated the expression of iNOS and its relation to inflammatory
cells in atheroma. New Zealand White rabbits were fed 1 of 4 diets:(i) normal diet for 9
weeks;(ii) normal plus 1% cholesterol diet (atherogenic diet) for 9 weeks;(iii) atherogenic
diet for 9 weeks, then normal diet for 9 weeks;(iv) atherogenic diet for 9 weeks, then the …