Identification of human and mouse HIRA-interacting protein-5 (HIRIP5), two mammalian representatives in a family of phylogenetically conserved proteins with a role …
S Lorain, Y Lécluse, C Scamps, MG Mattéi… - Biochimica et Biophysica …, 2001 - Elsevier
The human HIRA protein is encoded from a region of chromosome 22q that is critical for the
DiGeorge syndrome and the velocardiofacial syndrome. We have previously reported that it
directly interacts with core histones, with a novel histone-binding protein, HIRIP3, and during
mouse embryogenesis, with the developmentally regulated homeodomain protein Pax3,
suggesting a promoter-targeted function at the chromatin level. We here report on HIRA-
interacting protein 5 (HIRIP5), a small acidic protein that interacted with HIRA in a double …
DiGeorge syndrome and the velocardiofacial syndrome. We have previously reported that it
directly interacts with core histones, with a novel histone-binding protein, HIRIP3, and during
mouse embryogenesis, with the developmentally regulated homeodomain protein Pax3,
suggesting a promoter-targeted function at the chromatin level. We here report on HIRA-
interacting protein 5 (HIRIP5), a small acidic protein that interacted with HIRA in a double …