New indices of ischemic heart disease and aging: studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell …

N Morisaki, I Saito, K Tamura, J Tashiro, M Masuda… - Atherosclerosis, 1997 - Elsevier
It is known that the expression of intercellular adhesion molecule-1 (ICAM-1) and vascular
cell adhesion molecule-1 (VCAM-1) on the surface of vascular endothelial cells is closely
related to the formation of early atherosclerotic lesions. In this study, serum soluble ICAM-1
(sICAM-1) and soluble VCAM-1 (sVCAM-1) were determined by sandwich ELISA both in
normal healthy individuals (n= 114) and in patients with hypercholesterolemia (HC, n= 112)
or ischemic heart disease (IHD, n= 38) to clarify the significance of the soluble forms of the …