Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation
A Bröijersén, F Karpe, A Hamsten, AH Goodall… - Atherosclerosis, 1998 - Elsevier
The present study was conducted to determine whether alimentary lipemia alters platelet
activity in vivo. Normolipidemic volunteers were given a fatty meal and platelet function was
assessed before, and 3 and 6 h after the meal. Platelet aggregability and secretion was
determined using whole blood flow cytometry (expression of platelet P-selectin and
fibrinogen binding), filtragometry ex vivo (reflecting platelet aggregability in vivo) and by
measurements of platelet specific products in plasma (β-thromboglobulin and platelet factor …
activity in vivo. Normolipidemic volunteers were given a fatty meal and platelet function was
assessed before, and 3 and 6 h after the meal. Platelet aggregability and secretion was
determined using whole blood flow cytometry (expression of platelet P-selectin and
fibrinogen binding), filtragometry ex vivo (reflecting platelet aggregability in vivo) and by
measurements of platelet specific products in plasma (β-thromboglobulin and platelet factor …