Placental transport rather than maternal concentration of amino acids regulates fetal growth in monochorionic twins: implications for fetal origin hypothesis
R Bajoria, SR Sooranna, S Ward, S D'Souza… - American Journal of …, 2001 - Elsevier
Objective: The cause of discordant growth in monochorionic twins is not clear. We
hypothesize that growth restriction of 1 monochorionic twin is due to fetal under-nutrition.
Study Design: We measured plasma amino acid concentrations by high performance liquid
chromatography in maternal venous and fetal umbilical cord venous blood samples that
were collected at birth from gestational age–matched monochorionic twins (n= 14) with a
birth weight discordance of≥ 20%. The concordant monochorionic twins with birth weight …
hypothesize that growth restriction of 1 monochorionic twin is due to fetal under-nutrition.
Study Design: We measured plasma amino acid concentrations by high performance liquid
chromatography in maternal venous and fetal umbilical cord venous blood samples that
were collected at birth from gestational age–matched monochorionic twins (n= 14) with a
birth weight discordance of≥ 20%. The concordant monochorionic twins with birth weight …