Cell surface receptors and ectoenzymes in mesangial cells.

R Ardaillou, D Chansel, V Stefanovic… - Journal of the American …, 1992 - journals.lww.com
Mesangial cells possess a variety of receptors for hormones and autacoids. They are also
equipped with ectoenzymes whose function may be to control the availability of autacoids
and hormones at their receptor sites. Several examples are considered. Receptors for
angiotensin II (AII) are present both on murine and human mesangial cells. One single
group of receptors has been demonstrated in each of these preparations. Mesangial cell AII
receptors are linked to phospholipase C via a G protein. They belong to the AT1 subtype …