Ecto-nucleotidases—molecular structures, catalytic properties, and functional roles in the nervous system

H Zimmermann, N Braun - Progress in brain research, 1999 - Elsevier
Publisher Summary This chapter discusses the molecular structures, catalytic properties,
and functional roles of ecto-nucleotidases in the nervous system. Only one ecto-5'-
nucleotidase gene is known in vertebrates. Ecto-5'-nucleotidase plays a critical role in the
extracellular hydrolysis cascade of nucleotides and in neural development. Several families
of ectonucleotidases function in the nervous system. They differ in their catalytic and other
functional properties and consist of several members each. The chapter presents that …