Immunosuppression of cell-and serum-mediated tumour-associated immunity in prostatic cancer by human seminal plasma

RJ Ablin, RA Bhatti, IM Bush, PD Guinan - European Journal of Cancer …, 1980 - Elsevier
The immunosuppressive properties of the hormonal and/or secretory milieu or tumour-
elaborated factors (in the case of carcinoma) of the prostate have been hypothesized as
contributory to the natural history of prostatic cancer. The effect of normal human seminal
plasma (HuSPl) on immunity to tumour-associated antigens and the 'arming'of normal
peripheral blood leukocytes (PBL) by cytophilic antibody in the sera of patients with prostatic
cancer have been evaluated by leukocyte adherence inhibition, a suggested in vitro …