Oxidized lipids as mediators of coronary heart disease
M Navab, SY Hama, ST Ready, CJ Ng… - Current opinion in …, 2002 - journals.lww.com
M Navab, SY Hama, ST Ready, CJ Ng, BJ Van Lenten, H Laks, AM Fogelman
Current opinion in lipidology, 2002•journals.lww.comWe and others have hypothesized that HDL and LDL-derived oxidized phospholipids may
be part of a system of nonspecific innate immunity. We therefore propose that determination
of HDL capacity against LDL oxidation and the detection of proinflammatory HDL may be a
useful marker of susceptibility to atherosclerosis.
be part of a system of nonspecific innate immunity. We therefore propose that determination
of HDL capacity against LDL oxidation and the detection of proinflammatory HDL may be a
useful marker of susceptibility to atherosclerosis.
Summary
We and others have hypothesized that HDL and LDL-derived oxidized phospholipids may be part of a system of nonspecific innate immunity. We therefore propose that determination of HDL capacity against LDL oxidation and the detection of proinflammatory HDL may be a useful marker of susceptibility to atherosclerosis.
Lippincott Williams & Wilkins