Spatiotemporal expression of angiogenesis growth factor receptors during the revascularization of regenerating rat liver

MA Ross, CM Sander, TB Kleeb, SC Watkins… - Hepatology, 2001 - journals.lww.com
Regenerating liver was evaluated for the spatiotemporal expression of angiogenic growth
factor receptors on endothelial cell (EC) membranes during revascularization resulting from
70% partial hepatectomy (PHx). Fractions enriched in EC membranes were examined by
Western blot for angiogenic growth factor receptor expression from 1 to 14 days after PHx.
Increases in vascular endothelial growth factor (VEGF) receptors Flt-1 and Flk-1/KDR,
angiopoietin receptors Tie-1, Tie-2, and platelet-derived growth factor receptor beta (PDGF …