Elastin degradation in abdominal aortic aneurysms
JS Campa, RM Greenhalgh, JT Powell - Atherosclerosis, 1987 - Elsevier
Histological sections through the walls of abdominal aortic aneurysms showed scarce and
disrupted elastic tissue. The elastin content of the aneurysmal aortic media was only
8.1±3.2% dry defatted weight (n= 11). The elastin content of grossly normal age and
anatomically matched aortic media was 35.0±3.2% dry weight (n= 4) and the elastin content
of severely artherosclerotic, stenosed infrarenal aortic media was 22.0±7.2% dry weight (n=
6). There was an inverse correlation of elastin content with the elastinolytic activity of aortic …
disrupted elastic tissue. The elastin content of the aneurysmal aortic media was only
8.1±3.2% dry defatted weight (n= 11). The elastin content of grossly normal age and
anatomically matched aortic media was 35.0±3.2% dry weight (n= 4) and the elastin content
of severely artherosclerotic, stenosed infrarenal aortic media was 22.0±7.2% dry weight (n=
6). There was an inverse correlation of elastin content with the elastinolytic activity of aortic …