Low frequency of cirrhosis in a hepatitis C (genotype 1b) single-source outbreak in Germany: a 20-year multicenter study
M Wiese, F Berr, M Lafrenz, H Porst, U Oesen - Hepatology, 2000 - Elsevier
From August 1978 until March 1979, 14 batches of anti-D immune globulin contaminated
with hepatitis C virus (HCV) genotype 1b (20,000-480,000 copies/dose) from a single
erythrocyte donor had been administered for prophylaxis of rhesus isoimmunization
throughout East Germany. All 2,867 women involved had been recalled after January 12,
1979 for repeated screening of alanine transaminase (ALT). They were prospectively
followed in regional centers. We have reexamined a cohort of 1,018 women (median age …
with hepatitis C virus (HCV) genotype 1b (20,000-480,000 copies/dose) from a single
erythrocyte donor had been administered for prophylaxis of rhesus isoimmunization
throughout East Germany. All 2,867 women involved had been recalled after January 12,
1979 for repeated screening of alanine transaminase (ALT). They were prospectively
followed in regional centers. We have reexamined a cohort of 1,018 women (median age …